ReOxy® is the only device of it’s kind with clinically proven benefits.

With numerous clinical trials successfully completed and several ongoing, the clinical efficacy of the ReOxy® treatment method has been consistently demonstrated. These results solidify ReOxy®’s position as an innovative and trusted solution in the market.

Clinical evidence

CategoryTitleYearAuthorsJournalLangLink
Respiratory healthIntermittent Hypoxic-Hyperoxic Training During Inpatient Rehabilitation Improves Exercise Capacity and Functional Outcome in Patients With Long Covid: Results of a Controlled Clinical Pilot Trial2024Wolfram Doehner, Azadeh Fischer, Banafsheh Alimi, Jasmin Muhar, Jochen Springer, Christoph Altmann, Per Otto SchuellerJournal of Cachexia, Sarcopenia and MuscleENG
MetabolismIntermittent Hypoxic-Hyperoxic Exposures Effects in Patients with Metabolic Syndrome: Correction of Cardiovascular and Metabolic Profile2022Afina Bestavashvili, Oleg Glazachev, Alexander Bestavashvili, Alexander Suvorov, Yong Zhang, Xinliang Zhang, Andrey Rozhkov, Natalia Kuznetsova, Chavdar Pavlov, Dmitriy Glushenkov  and Philippe KopylovBiomedicinesENG
Aging | cognitive functionsEffects of Intermittent Hypoxia-Hyperoxia Exposure Prior to Aerobic Cycling Exercise on Physical and Cognitive Performance in Geriatric Patients—A Randomized Controlled Trial2022Tom Behrendt, Robert Bielitzki, Martin Behrens, Oleg S Glazachev, Lutz SchegaFrontiers in PhysiologyENG
Respiratory healthInterval hypoxic-hyperoxic training in rehabilitation of patients with osteoarthritis and post-covid syndrome 2022E. Orlova, N. Lyamina, I. Pogonchenkova, N. SkorobogatykhAnnals of the Rheumatic DiseasesENG/RUSAbstract | Original article
MetabolismThe Effects of Intermittent Hypoxic–Hyperoxic Exposures on Lipid Profile and Inflammation in Patients With Metabolic Syndrome2021Bestavashvili Afina A, Glazachev Oleg S., Bestavashvili Alexander A., …and Kopylov Philippe Yu Frontiers in Cardiovascular MedicineENG
Cardiovascular healthIntermittent Hypoxia–Hyperoxia Conditioning Improves Cardiorespiratory Fitness in Older Comorbid Cardiac Outpatients Without Hematological Changes: A Randomized Controlled Trial2018Elena Dudnik, Elena Zagaynaya, Oleg S. Glazachev, and Davide SustaHigh Altitude Medicine & BiologyENG
Cardiovascular healthIntermittent systemic hypoxic– hyperoxic training for myocardial protection in patients undergoing coronary artery bypass surgery: first results from a single-centre, randomised controlled trial 2018Denis S Tuter, Philippe Y Kopylov, Abram L Syrkin, Oleg S Glazachev, Roman N Komarov, Andrei I Katkov, Ljudmila P Severova, Ekaterina V Ivanova, Young Zhang, Hugo SanerOpen HeartENG
SportsA programme based on repeated hypoxia-hyperoxia exposure and light exercise enhances performance in athletes with overtraining syndrome: a pilot study2017Davide Susta, Elena Dudnik and Oleg S. Glazachev Clinical Physiology and Functional ImagingENG
Aging |cognitive functionsIntermittent hypoxic–hyperoxic training on cognitive performance in geriatric patients 2017Urike Bayera, Rudolf Likarb, Georg Pintera, Haro Stettnerc, Susanne Demscharb, Brigitte Trummerb, Stefan Neuwerschb, Oleg Glazachevd, Martin Burtscher Otto-von-Guericke Alzheimer’s & Dementia: Translational Research and Clinical Interventions ENG
Cardiovascular healthAdaptations following an intermittent hypoxia-hyperoxia training in coronary artery disease patients: a controlled study2016Oleg Glazachev, Phylipp Kopylov, Davide Susta, Elena Dudnik, Elena ZagaynayaClinical CardiologyENG
Cardiovascular healthEffect of interval hypoxic-hyperoxic training on exercise tolerance in patients with stable effort angina of Il—III functional classes against the backdrop of an optimal drug therapy2015E.E. Zagaynaya, F.YU. Kopylov, O.S. Glazachev, E.N. Dudnik, A.A. Bykova, A.L. SyrkinCardiology and cardiovascular surgeryENGOriginal article
SportsAdaptation to interval hypoxia- hyperoxia improves exercise tolerance in professional athletes: experimental substantiation and applied approbation 2014Yuriy Arkhipenko, Irina Vdovina, Nadezhda Kostina, Tatyana Sazontova, Oleg GlazachevEuropean Scientific Journal ENG
Cardiovascular healthInterval normobaric hypoxic-hyperoxic training increases exercise tolerance in patients with coronary artery disease2013O. Glazachev, Y.U. Pozdnyakov, A. Urinskiy, E. DudnikEuroPreventENG / RUSAbstract | Original article
Cardiovascular healthAdaptation to intermittent hypoxia-hyperoxia as cardio-protective technology in patients with coronary artery disease2012O. Glazachev, Y.U. Pozdnyakov, A. Urinskiy, A. Platonenko, G. SpirinaCad EuroENG / RUSAbstract | Original article
MetabolismThe effect of hypoxic–hyperoxic preconditioning on cardiometabolic risk-factors and gut hormones in patients with the metabolic syndrome2012O. Glazachev, H. Dudnik, L. Zvenigorodskaya, A. Platonenko, G. Spirina, T. MischenkovaECO CongressENG / RUSAbstract | Original article

Systematic review mentioning ReOxy®

CategoryTitleYearAuthorsJournalLangLink
MetabolismEffectiveness of Intermittent Hypoxia–Hyperoxia Therapy in Different Pathologies with Possible Metabolic Implications2023Andreea-Bianca Uzun, Mădălina Gabriela Iliescu, Liliana-Elena Stanciu, Elena-Valentina Ionescu, Rodica Ana Ungur, Viorela Mihaela Ciortea,  Laszlo Irsay, Irina Motoașcă , Marius Nicolae Popescu , Florina Ligia Popa, Loredana Pazara, Doina-Ecaterina TofoleanMetabolitesENG
Cardiovascular healthIntermittent hypoxia conditioning as a potential prevention and treatment strategy for ischemic stroke: Current evidence and future directions2022Honghua Yuan, Jia Liu, Yuhang Gu, Xunming Ji and Guangxian NanFrontiers in NeuroscienceENG
AgingEffects of Intermittent Hypoxia in Training Regimes and in Obstructive Sleep Apnea on Aging Biomarkers and Age-Related Diseases: A Systematic Review2022Belay Tessema, Ulrich Sack, Brigitte König, Zoya Serebrovska Frontiers in Agining NeuroscienceENG
SportEffects of Intermittent Hypoxia–Hyperoxia on Performance- and Health-Related Outcomes in Humans: A Systematic Review2022Tom Behrendt , Robert Bielitzki, Martin Behrens, Fabian Herold and Lutz SchegaSports Medicine – OpenENG

The company benefits from the expertise of a long-standing Scientific Advisory Board composed of leading EU and UK cardiologists, specialists in hypoxia and altitude medicine, biostatisticians, and healthcare organization experts. AiMediq collaborates with a robust consortium of prominent research institutions, universities, clinics, and professional associations across Europe and the UK, including the Heart Failure Association of the ESC and the World Heart Federation, among others.

ReOxy® is the only device of it’s kind
with clinically proven benefits.

Reach out to us or discover more.